Williams, DarylAlzoghaibi, Lama2025-11-202025MLA 9nonehttps://hdl.handle.net/20.500.14154/77067This study quantifies and compares the moisture vapor transmission loss and moisture vapor permeability of various alginate wound dressings on the market, to best match their uses for specific wound types and depths. MVTR and MVP values are extrapolated from diffusion plots produced using the dynamic vapor sorption analyser via the gravimetric method. The DVS analyser was utilised to quantify moisture loss and gain of the wound dressings sensitive to the 4th decimal point, at average body temperature, varying relative humidity to emulate the environment in which its used.Precise and sensitive quantification of the moisture migration behavior of alginate moist wound dressings within an environment analogous to one of its end use is challenging to simulate, largely due to alginates’ high susceptibility to swelling. This study utilised the gravimetric method, chiefly the dry cup method outlined by the ASTM E 96 standard, to investigate and compare the rate of moisture vapor transmission, %moisture content, and permeability parameters through the moist wound dressings: Algisite M, Cutiderm, Kaltostat and Tegaderm in different simulated environments for accurate characterisation within a simulated environment closely resembling the biological context of their application, at 37 °C and RH% conditions adjusted based on the data to be extracted being diffusion or water sorption.17enmoisture migrationMVTRMVTR measurementMVTR quantificationmoisturemoisture vapor transmission ratewvtrwater vapor transmission ratealginatealginate wound dressingwound dressingmoist wound healingDVSDynamic vapor sorptiondynamic vapor sorption analysergravimetric methodmoist wound healing environmentdry cup methoddesiccant methodbiological conditionsalgisite Mcutidermkaltostattegadermsemipermeable filmrelative humidityRH%diffusionexudatewater sorptionwater sorption isothermpayne cellmvpmoisture vapor permeailitydiffusion plotpermeancetewltrans epidermal water lossThesis