Dr. Zubair AhmedMAJED FAHAD ABDULLAH ALOBAID2022-05-292022-05-29https://drepo.sdl.edu.sa/handle/20.500.14154/45705Background ABSTRACT Tranexamic acid (TXA) is an Antifibrinolytic agent and time-dependent drug that increases positive outcomes when used within the first three hours after an injury. TXA is administered to traumatic brain injury (TBI) patients in a pre-hospital setting to stabilise and prevent intracranial haemorrhage. A systematic review was conducted to investigate the impacts of pre-hospital administration of TXA in TBI patients.en