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Strategic, Commercial and Financial Analysis and Valuation of an approved Stock Market Listed Company.
(Aston University, 2023-12-14)
A detailed report for analysing a listed corporation, Reckitt Benckiser Group PLC. Thus, the purpose of this report is to give justifications and a recommendation on whether to invest in Reckitt Benckiser Group or not. To be able to reach such a recommendation, the group will be strategically and financially analyzed and valued.
Digital Currencies: Approaches to Regulation in International Financial Law
(The University of Manchester, 2023-11-29)
In an era where the adage 'cash is king' is increasingly challenged by digitalisation, the rise of digital currencies underscores a tectonic shift in international financial systems. From the innovative inception of Bitcoin's decentralised blockchain to the advent of stablecoins and Central Bank Digital Currencies (CBDCs), the landscape of monetary transactions is undergoing unprecedented change. Despite their rapid adoption and potential for reshaping the global financial architecture, digital currencies present unique regulatory conundrums. These challenges range from the inherent decentralisation that disrupts traditional oversight mechanisms to the potential misuse of pseudonymity and cross-border operability challenges. Drawing upon the evolution from Bitcoin to CBDCs, this dissertation interrogates how international financial law can adapt to this burgeoning realm. Exploring various regulatory stances adopted globally reveals the opportunities and pitfalls of differing approaches. While some nations embrace a laissez-faire attitude, fostering innovation but potentially overlooking risks, others tread a restrictive path, prioritising security over potential technological advancements. Amid these divergent pathways lies the necessity for robust, adaptive, and anticipatory regulatory strategies. By juxtaposing legal precedents with current developments, this study offers a holistic view of the digital currency domain, culminating in policy recommendations integrating cutting-edge technology, environmental considerations, and international collaboration. As the world ventures into this digital currency-driven future, the role of international financial law becomes crucial – not just as a guardian of financial stability but as a beacon guiding towards innovation, inclusivity, and systemic harmony.
Usage of Domestication and Foreignization in Arabic Translation Of China Achebe's Things Fall Apart
(University of Salford, 2011)
The main objective of this research is to investigate the use of domestication and foreignization in the Arabic translations of Chinua Achebe's English novel Things Fall Apart. Through comparison of the two Arabic translations of Chinua Achebe's English novel Things Fall Apart, and the strategies that have been employed by the translators Ahmad Khalefah (1990) and Sameer Nassar (2002). The study starts with an explanation of the strategies of translation, in particular domestication and foreignization .This paper also examines the strategies and methods the translators use in translating cultural references. This study also analyses the cultural elements that are found in the novel in relation to Newmark (1988) division of culture categories. The study also explores the procedures that have been used by the translators of the novel in translating the cultural concept.
Evaluating C-reactive protein (CRP) and Interferon gamma-induced protein 10 (IP-10) as Biomarkers for Tuberculosis Treatment Monitoring: A Systematic Review on Adult Pulmonary Tuberculosis Treatment
(Keele University, 2023-09-05)
Background: Tuberculosis (TB) is an enduring global health menace that predominantly affects low- and middle-income nations. Despite medical advancements, TB continues to claim numerous lives every year, necessitating innovative solutions to enhance treatment and monitoring. Conventional strategies for monitoring the progress and outcomes of TB treatment often face challenges, especially in resource-limited settings. These limitations include delayed results, invasive procedures, and the need for sophisticated equipment. Consequently, the medical community is in dire need of efficient and reliable biomarkers that can serve as indicators of treatment response and disease progression. Objectives: The primary aim of this review was to meticulously investigate the potential effectiveness of C-reactive protein (CRP) and Interferon gamma-induced protein 10 (IP-10) as biomarkers for TB treatment monitoring. Specifically, this review sought to answer: "How effective are CRP and IP-10 in tracking treatment response in adults undergoing therapy for active pulmonary tuberculosis?" Methods: Guided by the stringent PRISMA 2020 statement guidelines, an exhaustive search of the literature was conducted, focusing on studies that shed light on CRP and IP-10 as prospective biomarkers for TB treatment tracking. Multiple databases were scoured, and a rigorous selection protocol was established, filtering out studies based on relevance, language, and other criteria. This meticulous approach ensured the inclusion of only the most pertinent studies that contribute significantly to the research question. Results: Out of an initial pool of 39 articles, six pivotal studies were selected for in depth review. These studies spanned a diverse range of geographical territories, from South Korea and Uganda to India and Gambia, offering a broad spectrum of insights. The collated results indicated that biomarker concentrations, notably IP-10 and CRP, exhibited significant fluctuations in sync with TB treatment stages and overall disease diagnosis. The consistency of IP-10 levels in monitoring therapeutic response was particularly pronounced in patients diagnosed with active TB. On the other hand, CRP levels displayed a discernible downward trend as the treatment progressed, underscoring its potential as a reliable indicator of therapeutic effectiveness. However, certain studies also illuminated the circumscribed role of IP-10 as a biomarker in regions heavily burdened with TB. This highlighted the imperative for context-specific evaluation before the widespread adoption of these biomarkers. Conclusions: The findings of this review underscore the promising potential of both CRP and IP-10 as innovative biomarkers for TB treatment monitoring. While IP-10 exhibits a pronounced capability in differentiating between active and latent TB infections, CRP's consistent decline during treatment suggests its pivotal role in evaluating therapeutic efficacy. Nevertheless, the practical adoption of these biomarkers in real-world scenarios mandates further extensive research, comprehensive validation trials, and tailored evaluations to account for regional and demographic variations. The incorporation of such biomarkers could revolutionize TB treatment monitoring, offering rapid, reliable, and non-invasive methods that could be particularly beneficial in resource-constrained settings.
Micromechanical Analysis of Hybrid Composites
(The University of Manchester, 2023-11-28)
Hybrid composites, composed of two or more fibre types within a common matrix, offer mechanical characteristics that may not be attainable with single-fibre composites. This study investigated the micromechanical behaviour of hybrid composites using the unit cell approach, studying the synthetic–synthetic, natural–natural, and natural–synthetic hybridisation cases, hence, the influence of combining the different fibres, and the effect of varying volume fractions of fibres of the hybrid composites. Single fibre composites, carbon, glass, hemp, and ramie were analysed first to investigate the performance of the single fibres; the analyses showed that glass fibre-reinforced polymer had the highest transverse and shear moduli, whereas hemp fibre had the highest Poisson's ratio. Carbon and glass fibres showed better stress distribution for synthetic-synthetic fibre cases, whereas hemp-ramie's natural–natural pairing was less optimal. Among the natural–synthetic combinations, hybrid composites with hemp, particularly when combined with glass, showed increased stress distribution over those incorporating ramie. Despite the slightly lower performance compared to carbon, hemp showed to be a cost-effective alternative to carbon fibre, especially when combined with glass. On the other hand, introducing ramie into the hybrid composites led to a decrease in the effective transverse, shear moduli and Poisson's ratio of the hybrid composites when combined with other fibres. Therefore, hemp was shown to be a more optimal natural fibre to replace carbon fibres, whereas ramie may be optimal for less mechanically demanding applications.