Browsing by Author "Alamri, Aisha"
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Item Restricted Essays on Sustainable Growth and Development in GCC Countries(Howard University, 2024-06-28) Alamri, Aisha; Kato, MikaThis article analyzes the effects of natural resources and location determinants on foreign direct investment (FDI) in the Gulf Cooperation Countries (GCC) using panel data from 2000–2022. Using oil production, oil reserves, and oil production in relation to oil reserves as a means to measure natural resources, I determine fixed effect (FE) and random effect (RE) analyses based on the Hausman test. This study concluded that oil production, and oil production relative to oil reserves discouraged FDI in GCC countries. Furthermore, the study concludes that there is a positive relationship between oil prices, infrastructure, and FDI, while human capital has no influence on FDI.42 0Item Restricted Phenotypic and Genotypic Characterization of Multi Drug Resistant Acinetobacter baumannii in King Fahad Hospital of the University in Al Khobar, KSA.(Imam Abdulrahman Bin Faisal University, 2020) Al-Quraian, Amerah Mohammed Saleh; Alamri, AishaBackground: Acinetobacter baumannii, a bacterial species which demonstrates an elevated wide range, multidrug resistance to commonly prescribed antibiotics, has been linked to recent major global outbreaks, raising a major clinical concern. Its reduced antibiotic susceptibility is closely related to the acquisition of a potent carbapenemase, and/or intrinsic gene ‘’over expression’’ through insertion sequences. Hence, this study aimed at investigating the antimicrobial susceptibility and molecular mechanisms underlying β-lactam resistance in A. baumannii, isolated at an academic medical center.Methods: To understand the basis of resistance, 103 multi-drug resistant (MDR) A. baumannii isolates were collected, their antibiotic susceptibility was tested phenotypically (Vitek II), and then molecular analyses was performed, by testing a range of commonly encountered carbapenemases—OXA-51, OXA-23, NDM, VIM, and KPC.Results: All strains demonstrated pan-resistance to most of the advanced antibiotics tested, including piperacillin/tazobactam, ceftazidime, cefepime, and ciprofloxacin. Moreover, majority of isolates exhibited resistance to imipenem (98.1%) and trimethoprim (90.3%). Approximately 50% of the strains showed meropenem, amikacin, and gentamycin resistance; however, lower resistance rate to tigecycline (4.9%) was noted. Moreover, isolates contained potent carbapenemases such as the intrinsic OXA-51 (89.3%), as well as the acquired resistant genes OXA-23 (68.9%), NDM (84.5%), and VIM (88.3%). The insertion sequence element ISAba1 was only detected in 35.9% of the strains.Conclusion: Potent resistant genes known to be carried on mobile genetic elements that aid the spread of highly resistant phenotypes were observed in a majority of isolates. These findings enforce the need for vigilant infection control measures and continuous surveillance.13 0