Browsing by Author "Alanazi, Jawaher"

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The effectiveness and safety of the Ketogenic Diet on overweight and obese women with Polycystic Ovary Syndrome on anthropometric, endocrine and metabolic parameters: A Systematic Review
(Saudi Digital Library, 2023-12-01) Alanazi, Jawaher; McCullough, Fiona
Background: Polycystic Ovary Syndrome (PCOS) is a multifaceted endocrine disorder that affects reproductive-aged women. This condition is frequently associated with obesity, hyperinsulinemia, and insulin resistance. The ketogenic diet (KD), a high-fat, low-carbohydrate dietary approach, has gained interest for its potential effects, not only in the treatment of obesity but also in related metabolic disorders. Objective: The current systematic review aimed to evaluate the effectiveness of KD on body mass index (BMI) and body weight (BW), as well as endocrine parameters including menstrual cycle, testosterone (TST), luteinizing hormone (LH), follicle- stimulating hormone (FSH), LH/FSH, and metabolic parameters such as triglycerides, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and the safety of KD in women with PCOS. Methodology: A systematic search of four databases Embase (Ovid), NUsearch, ScienceDirect and PubMed for full-text publications published in English between 2005 and 2023 was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses. Randomised controlled trials and cohort studies that investigated the effects of KD on women with PCOS aged 18–45 with a BMI > 25 were eligible. Result: Seven trials were identified and evaluated. All studies showed significant BMI and BW (the mean weight loss was -13.02%) reductions with the KD. Among the analysed studies, four reported favourable outcomes in terms of ameliorating menstrual cycle regularity through KD utilisation. Changes in TST were significant in three investigations, while three others revealed no such effect. Three studies reported significant changes in LH, FSH, and LH/FSH ratios, while one study found none. Changes in TG, LDL, and HDL were observed in two trials, only one study reported a change in TG. No significant metabolic parameters were found in two studies. All three trials concluded that the KD was safe for obese women with PCOS. Conclusion: Women with PCOS who are classified as overweight or obese had a change in both BW and BMI, subsequently, improving the menstrual cycle, as well as the TST, LH, FSH, and LH/FSH ratio and metabolic markers showed potential improvements with no reported adverse effects.
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THE IMPACT OF INDUSTRY 4.0 TECHNOLOGIES ON SUPPLY CHAIN RESILIENCE IN SAUDI ARABIA
(Saudi Digital Library, 2025) Alanazi, Jawaher; Greasley, Andrew
This dissertation examines the impact of Industry 4.0 technologies on supply chain resilience in Saudi Arabia, where initiatives such as Internet of Things and the Global Supply Chain Resilience Initiative (GSCRI) are central to industrial transformation. A systematic literature review (SLR) guided by the PRISMA framework was conducted, covering academic and grey literature published between 2020 and 2025. The search initially yielded 315 records; after applying inclusion and exclusion criteria, 26 studies were selected for detailed analysis. The findings indicate thatInternet of Things (AI), blockchain, the Internet of Things (IoT), and digital twins are the leading technologies supporting resilience capabilities, particularly in risk mitigation, operational continuity, agility, and sustainability. However, barriers such as high implementation costs, limited absorptive capacity, institutional inertia, and fragmented infrastructure constrain their full potential. This research contributes by integrating insights from policy initiatives, industry practices, and recent empirical studies to show how Industry 4.0 adoption strengthens resilience in supply chains within an emerging economy context. It underscores the strategic role of digital transformation in enabling continuity, flexibility, and sustainability. The study concludes with practical recommendations for policymakers and practitioners in Saudi Arabia, emphasizing the need to strengthen digital infrastructure, enhance workforce skills, and foster cross-sector collaboration. It also highlights avenues for future research, including empirical studies on digital maturity and comparative analyses across sectors and regions.
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