Browsing by Author "Alshehri, Areej"

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A Multi-Perspective Narrative Review of the Impact of Drug Recalls on Pharmaceutical Companies & Mitigation Strategies
(Saudi Digital Library, 2025) Alshehri, Areej; Catena, Rodolfo
Introduction: Drug recalls, though essential for public health protection, they trigger financial and reputational impacts on pharmaceutical companies. Aims: This narrative review study aim is to identify the financial and reputational impacts of drug recalls on major pharmaceutical companies, effective post-recall response strategies, and best practices for recall prevention. Methodology: A search was conducted using various electronic databases, including PubMed, Web of Science, Google Scholar, websites related to pharmaceutical companies, and news articles. Keywords related to recalls in pharmaceutical industry were used. This search was limited to literature published between 2014 and 2025. This review included original research articles, review articles, and case studies. Results: The review identified significant financial and reputational impacts resulting from drug recalls, including litigation costs, operational losses, and diminished brand trust. Identified effective recall strategies included regulatory compliance, transparent communication, contingency planning, delegated authority, recall simulations, insurance coverage (including Directors and Officers D&O), strong documentation, closed-loop recall systems, and diverse board leadership. Moreover, compliance with manufacturing standards, ongoing quality control, Quality by Design (QbD) adoption, system integration, and global recall databases, may prevent recalls. Conclusion: This review underscores the importance of strategic recall management, legal preparedness, and preventive quality measures. The ranitidine example illustrates how outcomes can vary based on company response, emphasising the need for proactive planning, effective management, and integrated systems to minimise harm and preserve corporate reputation.
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From decline to recovery: a meta-synthesis of the psychosocial impact of a traumatic birth
(Saudi Digital Library, 2023-11-20) Alshehri, Areej; Stockdale, Janine
Abstract - Summary of Dissertation Background: Traumatic birth is a potential risk factor for the development of mental health problems that affect both mothers and their infants. These problems can include post-traumatic stress disorder (PTSD), depression, anxiety, and bonding and attachment issues. A birth can be traumatic for many reasons, including the need for medical interventions, such as the use of forceps or vacuum extraction, and by prolonged labour or difficult delivery. Despite considerable research about women experiencing depression, anxiety, or PTSD as result of traumatic birth, little research has been conducted that focuses on the impact these birth experiences have on the psychological and social wellbeing of women during the postpartum period. This therefore represents the first qualitative review that updates and extends our understanding of how traumatic births affect women after childbirth. Aim: This review aims to explore the psychosocial effect of traumatic birth on maternal wellbeing in the postpartum period, and builds on the work of Fenech and Thomson (2014) to provide an up-to-date expansion of their initial meta-synthesis. Objectives: To answer the aim, the following objectives were set:  To source relevant and up-to-date evidence related to the psychosocial effects of traumatic birth  To provide an up-to-date synthesis of the evidence related to the psychosocial effects of traumatic birth  To outline the similarities and differences between the findings of the current review (2023) and those reported in Fenech and Thomson (2014). Methodology: Initial manual searches of Google Scholar, PROSPERO, ProQuest, and OPENGREY were conducted to identify any unpublished reviews or those still being undertaken as part of thesis or dissertation work. The main searches were carried out systematically 6 on six databases including Medline, Embase, PsychINFO, CINAHL, and Maternity & Infant Care, from 2014 to the present. The quality of the included studies was evaluated with the CASP tool. Findings: Seventeen qualitative studies that met the selection criteria and focused on the impact of traumatic birth were included in this review. The studies ranged from high to low methodological quality and the data they contributed was synthesized using a metaethnographic approach. Two themes emerged during the synthesis: “Being Out of Control", and "Taking Back Me". Conclusion: The review provides an update and expansion of the earlier evidence provided by Fenech and Thomson (2014) review, and found that traumatic births can have important negative as well as positive impacts on women's lives. The negative effects include post-traumatic stress disorder, anxiety, depression, and difficulty bonding with their baby. Positive outcomes include increased resilience, enhanced appreciation of life, and feeling more connected to their family. This review demonstrates the need for further research into the time it takes women to develop post-traumatic growth after traumatic births.
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