Browsing by Author "REHAB ABDULAZIZ AHMED ALDAHASH"

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Effect of Gallic and Ferulic Acids on Oxidative Phosphorylation on Candida albicans (spp A27 and SC5314) During the Yeast-to-Hyphae Transition
(Saudi Digital Library) REHAB ABDULAZIZ AHMED ALDAHASH; Dr. Vicki Schlegel
Candida albicans is a dormant commensal in the mucosa of healthy individuals but can become an opportunistic pathogen when the host microflora is compromised. It has been reported the most common cause of fungal infection among hospitalized U.S. patients, with elevated mortality rate. Candida species has been reported as resistant to antifungal drugs that increase the application of novel strategies to treat this infection. One of most natural compounds is phenolic that have gained attention as potential agents against fungi. C. albicans which has the ability to switch phenotype from yeast-to-hyphae cells, the most invasive form; therefore, therapies aiming to impair this morphologic transition can be promising against this fungus. The main objective of this work was to evaluate the ability of isolate phenols to prevent the yeast-to-hyphae transition of C. albicans by modulating the activity of the enzyme complexes involved in oxidative phosphorylation. Also, C. albicain species (SC5314 and A27) were significantly differently when it response to the OXPHOS respiration even though they showed similar morphologies. Cells were treated with certain concentrations of gallic and ferulic acid in isolation which prevent hyphal growth by 25-50 % were determined. Results showed that gallic and ferulic acids were inhibit the enzyme activity involved in oxidative phosphorylation of C. albicain (SC5314 and A27).
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NUTRITION KNOWLEDGE AND BEHAVIOR RELATED TO FAT INTAKE AMONG FOREIGN-BORN ARABIC-SPEAKING WOMEN
(Saudi Digital Library) REHAB ABDULAZIZ AHMED ALDAHASH; Dr. Megan S. Kelley
Background: Upon arrival in the United States, the health of most immigrant and refugee populations is better than that of the general United States population (Wieland et al., 2012). Nutrition knowledge is low among low-income women, which has led to a high burden of obesity among low-income and minority women in the United States (Laz et al., 2015). Methods: In this study, a mixed-method design was used. Forty participants visiting community-based organizations in Lincoln, NE, completed a survey to assess nutrition knowledge, behavior, and intention, applying the Transtheoretical Model of Behavior Change. Twenty respondents were foreign-born Arabic-speaking women, and twenty were native-born American women—two focus groups with foreign-born Arabic-speaking women and one with community-based organization workers. The quantitative data were analyzed using SPSS software, running a Mann-Whitney test, Kruskal-Wallis test, Spearman's R Correlation Coefficient, and chi-square test. For qualitative data, MAXQDA Qualitative Analysis Software was used. Lastly, a joint visual display integrated quantitative and qualitative data analysis. Results: No significant differences existed in the total score of nutrition knowledge, behavior, and intention related to fat intake between low income native-born American and foreign-born Arabic-speaking women. The more time foreign-born Arabic-speaking women spend in the United States, the more their nutrition behavior improves, and they become at a later stage of change behavior related to fat intake. Community-based organizations workers were working on providing some support and programs to those with some health issues and foreign-born Arabic-speaking women. However, they need more work with other organizations to improve those programs and be more effective. Conclusion: This study may contribute to the awareness of immigrants' diets and support the importance of maintaining their cultures following immigration in ways such as keeping traditional food. Foreign-born Arabic-speaking women looked for health awareness classes on several topics: nutrition or other diseases; improved lifestyle; plans to improve food distribution; and cooking.
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