SACM - United States of America
Permanent URI for this collectionhttps://drepo.sdl.edu.sa/handle/20.500.14154/9668
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Item Restricted The Relationship between Child Maltreatment, Religiosity, and Adult-onset Anxiety and Depressive Disorders among Participants in the Saudi National Mental Health Survey (SNMHS)(University of Washington, 2024) Gadi, Ghadah; Sharif, MienahThis dissertation explores the interrelationships among childhood maltreatment (CM), religiosity, and adult-onset depressive and anxiety disorders using data from the Saudi National Mental Health Survey (SNMHS). It addresses whether parental religiosity is associated with CM and differs by gender, the influence of CM on adult religiosity and its gender-dependence, and the association between CM and adult-onset anxiety and depressive disorders with religiosity as a moderating factor. The first study (Chapter 2) investigates the correlation between parental religiosity and CM, finding no overall significant association but a significant protective effect against CM, particularly physical abuse, among males. The second study (chapter 3) explores the impact of CM on adult religiosity, revealing no significant association or gender differences. The third study (Chapter 4) examines the link between CM and adult-onset anxiety and depressive disorders, with religiosity moderating these effects. Sexual abuse significantly increases the risk of depressive disorders, while physical abuse increases anxiety disorder risk. Seeking religious comfort moderates these associations. In conclusion, this dissertation highlights that parental religiosity generally protects against CM, especially physical abuse among males, while CM does not influence adult religiosity. CM is associated with higher risks of mental health disorders, with religious coping moderating these effects. The findings emphasize the need for culturally tailored interventions in Saudi Arabia to promote healthy religious parenting, encourage seeking professional help, and address cultural and gender dynamics influencing CM experiences and mental health outcomes.20 0Item Restricted DUAL BURDEN: HCV ANTIBODY POSITIVITY AND DEPRESSION DIAGNOSIS IN UNITED STATES ADULTS(New York University, 2024-06-24) Alserhani, Asma; Coyle, ChristianaBackground: Hepatitis C virus (HCV) infection and depression are significant public health concerns, with previous studies suggesting a complex relationship between the two conditions. This study aimed to investigate the association between HCV infection and depression among U.S. adults using a nationally representative sample. Methods: A cross-sectional analysis was conducted using data from the National Health and Nutrition Examination Survey (NHANES) 2015-2020. The study included 8,443 participants aged 18 years and above who completed the depression screening questionnaire and underwent HCV testing. Depression was assessed using the Patient Health Questionnaire-9 (PHQ-9), and HCV infection was determined by the presence of HCV RNA. Multivariable logistic regression was used to examine the association between HCV infection and depression while adjusting for potential confounders. Results: In the bivariate analysis, HCV-positive individuals had a significantly higher prevalence of depression compared to HCV-negative individuals. However, after adjusting for potential confounders in the multivariable analysis, the association between HCV status and depression was no longer statistically significant. Age, marital status, and smoking status emerged as significant predictors of depression in the adjusted model. Conclusion: This study found a significant association between HCV infection and depression in the bivariate analysis, but this relationship was attenuated after adjusting for potential confounders. The findings highlight the importance of considering multiple risk factors when assessing the mental health of individuals with HCV infection and underscore the need for targeted interventions to prevent and treat depression in high-risk groups.21 0Item Restricted The Relationship between Depression, Stress-Related Neurobiology, and Incident Heart Failure: Understanding the Neurobiological Mechanisms Underlying Exercise as a Preventive Measure(Saudi Digital Library, 2023-04) Alhamam, Abdulaziz Arif Abdulaziz; Tawakol, AhmedBackground: Depression is associated with risk of developing heart failure (HF). Also, higher stress-related neural activity (SNA) associates with subsequent risk of cardiovascular disease. We investigated whether depression predicts subsequent HF through heightened SNA. Methods: Individuals (N=102,028; median age 57 years; 42.6% male) enrolled in the Mass General Brigham Biobank were identified to study the association of depression and incident HF, subset of 1,227 who underwent clinically indicated 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) imaging were retrospectively identified. SNA was measured using validated methods, as amygdalar metabolic activity corrected for regulatory brain (i.e., medial prefrontal cortical) activity. Depression and subsequent development of HF was determined via medical record review using International Classification of Diseases 10 (ICD-10) codes. Survival analyses using Cox and Kaplan-Meier models were performed. Results: Over a median follow-up period of 3.5 (IQR 2.0-5.0) years, 2,631 (2.6%) individuals developed HF (717 Heart failure with reduced ejection fraction (HFrEF), 1,214 Heart failure with preserved ejection fraction (HFpEF)). Individuals with subsequent HF (versus no HF) had higher baseline SNA (mean Z-score 0.19 ± 1.07 versus -0.08 ± 0.99; p=0.005, adjusted for age and sex). SNA associated with subsequent HF when divided into tertiles (Figure 2B) and as a continuous measure (standardized HR [95% CI]: 1.40 [1.13-1.74], p=0.002, adjusted for age, sex, hypertension, hyperlipidemia, diabetes, and smoking). The association between depression and HF subtype was stronger for HFpEF (1.46 [1.28-1.65], p<0.001) than for HFrEF (1.09 [0.92 -1.3], p=0.32). Conclusion: In this retrospective study of individuals with depression have higher risk of incident HF through heightened SNA with a somewhat stronger association for HFpEF. Understanding the link between depression and subsequent HF may provide important insights into better HF prevention and management strategies.16 0Item Restricted EXAMINING THE RELATIONSHIP BETWEEN ACCULTURATIVE STRESS AND DEPRESSION AMONG SAUDI INTERNATIONAL STUDENTS IN THE USA(Saudi Digital Library, 2023-08) Shawly, Alaa; Delmonico, DavidThis quantitative study explored Saudi international students’ acculturation processes through an examination of the relationship between acculturative stress and depression among Saudi international students in the U.S. Moreover, the study also examined the role of social resources—social support and the use of counseling services—in mediating this relationship. Data was collected through an online survey from 103 Saudi international students enrolled at universities across the U.S. The survey included three scales: the Acculturative Stress Scale for Saudi International Students (ASSSIS) (Bashir & Khalid, 2020), the Beck Depression Inventory (BDI) (Beck et al., 1996), and LEVEL 2–Depression–Adult (PROMIS Emotional Distress– Depression–Short Form) (Nolte et al., 2019). To answer the research questions, several analyses were conducted. A correlation analysis was used to examine the relationship between acculturative stress and depression. In addition, a path analysis was conducted to explore the role of mediator variables—social support and the use of counseling services—in the relationship between acculturative stress and depression. Results reveal a significant relationship between acculturative stress and depression among Saudi international students in the U.S. It was also found that social support and the use of counseling services do not function as mediators for the association between acculturative stress and depression. The results emphasize the importance of the acculturation process for Saudi international students and its impact on depression. Implications for the field of counseling are provided as well as limitations of the current study and potential directions for future research. acculturative stress, depression, Saudi international students, social support, counseling services11 0