Saudi Cultural Missions Theses & Dissertations
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Item Restricted Antimicrobial Effects of Cold Atmospheric Plasma on Oral Biofilm Compared With No Treatment(Saudi Digital Library, 2023-08-07) Alshammari, Fahad Hashim; Ramage, GordonThis systematic review aimed to integrate existing knowledge regarding the antimicrobial potential of cold atmospheric plasma (CAP) in the context of oral biofilms, the cause of various oral infections. To achieve this, several databases, namely, MEDLINE, Embase, and Web of Science, were comprehensively searched for studies analysing the effects of CAP on oral biofilms. 11 studies are included to this review, and the outcomes of these studies were analysed and summarised using a modified version of the MINORS assessment tool because of the lack of a more suitable tool for in vitro studies. The findings of this review highlighted the remarkable antimicrobial potential of CAP against oral biofilms; however, considerable variation as noted in some specific parameters such as the type of gas, biofilm species, treatment duration, and voltage. Prior studies have suggested a 2-min threshold for efficacy; however, according to the findings of this review, this most studies indicated that CAP displayed efficient antimicrobial in less than 2 min. Additionally, the review indicated that CAP was adaptable and safe and has a minimal detrimental impact on nontarget tissues and oral materials. The review validated the antimicrobial effectiveness of CAP against oral biofilms, presenting it as a promising alternative to conventional techniques such as, mechanical debridement and antibiotics. Future in vivo and in vitro studies are warranted to validate these findings, create specific quality assessment tools for in vitro research, and explore the effects of CAP on nontarget tissues and common oral surfaces. These measures may help promote the use of CAP as an effective antimicrobial strategy in dentistry.6 0Item Restricted Development of 3D printed resin-based nanocomposites for dental prosthetic restorations(Saudi Digital Library, 2023) Aati, Sultan Yahya A; Fawzy, AmrProsthetic dentistry is an essential practice for maintaining the structure of the oral cavity. Resin-based materials have been clinically recognized as substitutes to restore lost teeth and function. 3D printing technology has significantly strengthened the production of dental prostheses due to its precision and economic advantages. The oral environment commonly subjects synthetic substitutes to excessive functional stress, causing degradation and clinical failure due to insufficient material integration and toughness. Additionally, the inherent physical properties of dental materials promote microbial adhesion and biofilm formation. Therefore, the development of 3D printed resin is imperative to enhance the clinical performance of dental restorations.42 0