Saudi Cultural Missions Theses & Dissertations
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Item Restricted The Relationship Between Caregivers' Contribution to Heart Failure Self-Care and Patient Self-Care: Exploring the Moderating Effect of Patient Cognitive Status(Case Western Reserve University, 2025-05) Aldossary, Heba Mohammed; Dolansky, Mary; Irani, Elliane; Schiltz, Nicholas; Sundaram, VarunHeart failure (HF) impacts millions worldwide and necessitates ongoing self-care, including maintenance, monitoring, and management, to prevent symptom worsening and hospitalization. Cognitive impairment, impacting memory, attention, and decision-making, is prevalent among patients with HF and may impede their self-care capabilities. In these instances, family caregivers frequently offer essential assistance. The effectiveness of this support in cases of cognitive impairment is not well established. Furthermore, other factors, including patient and caregiver self-efficacy, mental quality of life, and satisfaction with dyadic care may impact self-care, yet they remain insufficiently examined. This research employed a secondary analysis of data from 277 HF patient-caregiver dyads (N = 554) participating in a descriptive cross-sectional study conducted in Italy. Regression analyses, both multiple and moderated, were performed to investigate the relationships between caregiver contributions and patient HF self-care behaviors while evaluating the moderating effect of patient cognitive status and the impact of the covariates. The findings indicated that caregiver contributions were significant predictors of patient self-care in the domains of maintenance, monitoring, and management. Patient self-efficacy was identified as a significant and reliable predictor in all domains of self-care. The relationship between caregiver contribution and patient self-care maintenance and monitoring was significantly moderated by cognitive status, with caregiver support proving more effective for patients without cognitive impairment. Furthermore, caregiver satisfaction with dyadic care exhibited a negative correlation with self-care maintenance, while showing a positive correlation with self-care monitoring. The findings underscore the critical importance of caregiver support and patient self-efficacy in HF self-care, while also indicating that caregivers provide more support when there is no cognitive impairment. The results highlight the necessity of regular cognitive assessments and caregiver training when cognitive impairment exists to assist with HF self-management. The role of caregiver satisfaction indicates that relational dynamics may affect different aspects of self-care, necessitating further investigation. This research informs the creation of tailored interventions that include caregivers, with the goal of enhancing HF management.13 0Item Restricted Objective and Subjective Long-Term Cognitive Outcomes in COVID-19 Survivors Managed with ECMO: A Case Series(Royal Holloway, University of London, 2024) Alanazi, Abeer; Crabtree, AnnaCOVID-19 has been associated with significant health complications, including cognitive impairments, particularly among patients requiring intensive care interventions. A subset of these patients, especially those needing extracorporeal membrane oxygenation (ECMO), face heightened vulnerability due to prolonged Intensive Care Unit (ICU) stay and extended ECMO duration, placing them at an increased risk of developing post intensive care syndrome (PICS), a multifaceted condition that affects cognitive and psychological functions among other health- related domains. This study aims to investigate the cognitive screening outcomes and characteristics of cognitive impairments among COVID-19 survivors managed with ECMO, enhancing our understanding of cognitive outcomes in this high-risk group. Eighty-five COVID-19 patients who had been treated with ECMO were contacted after their ICU admission. The Telephone Montreal Cognitive Assessment (T-MoCA) was employed to detect cognitive impairment. Neuropsychological assessment was completed with ten survivors. A case series design was employed to characterise the cognitive profile of these ten COVID-19 survivors. The mean T-MoCA score for the 49 cohort was 16.20 (SD = 2.93), indicating cognitive impairment among COVID-19 survivors managed with ECMO. T-MoCA scores for the ten patients who completed neuropsychological assessments ranged from 10 to 19, with a mean score of 16.2 (SD = 2.94). The case series analysis demonstrated impairments across domains of attention, working memory, processing speed, and memory. Cognitive impairments are evident in COVID-19 survivors managed with ECMO, presenting cognitive profiles similar to those documented in acute respiratory distress syndrome (ARDS) patients (non-COVID-19). Key words: ICU, COVID-19, ECMO, Cognitive Impairment, PICS13 0