Saudi Cultural Missions Theses & Dissertations
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Item Restricted Knowledge and Acceptability of HPV Vaccination in Countries in the Eastern Mediterranean Region: A Systematic Review(University College London, 2024) Aboalaz, Amirah; Sonnenberg, PamBackground: Human Papillomavirus (HPV) is a significant cause of cervical cancer and may cause other cancers, including anal and penile cancers. Despite the availability of effective vaccines, the level of knowledge and acceptability of HPV vaccination varies widely across different regions. This systematic review focuses on the Eastern Mediterranean Region (EMR) to evaluate the current state of awareness and vaccine acceptability. Methods: A systematic review was conducted following PRISMA guidelines, with a comprehensive search across Embase, Scopus, PubMed, and Web of Science for studies published between January 1, 2008, and March 30, 2024. Inclusion criteria were cross-sectional studies conducted in the EMR that included questions on HPV awareness, vaccine awareness, the link between HPV and cervical cancer, and vaccine acceptability. Studies were assessed for quality using the Joanna Briggs Institute (JBI) critical appraisal checklist. Results: A total of 815 studies were identified and after screening and quality appraisal, a total of 36 studies from 14 countries in the EMR were included. The review revealed low levels of awareness about HPV and its vaccine, with median awareness levels at 35.05% for HPV infection and 31.8% for the HPV vaccine. The median acceptability level for the HPV vaccine was higher, at 54.05%. Knowledge about HPV was found to be correlated with higher vaccine acceptability. Conclusion: The findings highlight the need for targeted public health interventions to improve HPV vaccination knowledge and acceptability in the EMR. Strategies may include robust educational campaigns, integration of HPV education into school curricula, community engagement, and training of healthcare providers. Policy interventions to make the vaccine more accessible and affordable are also crucial. Addressing these challenges through comprehensive and multi-faceted approaches can significantly enhance vaccine uptake and reduce the burden of HPV-related diseases in the region.21 0Item Restricted Prevalence and Risk Factors of Human Papilloma Virus (HPV) Infection in Saudi Arabia: An Extended Literature Review(SWANSEA UNIVERSITY, 2024-09-21) AlKhuraym, Nasser; Pockett, RhysAbstract The Human Papillomavirus (HPV) infection is a considerable public health risk worldwide, including in Saudi Arabia, where around 358 women are diagnosed each year, resulting in 179 fatalities due to HPV-related malignancies. More than 10.7 million women aged 15 and older are susceptible to HPV infection and its related malignancies. The prevalence of HPV among women in Saudi Arabia is estimated at 2.5%, with HPV-related malignancies constituting 72.4% of cases in the region. Sexual practices constitute a significant risk factor for HPV infections. Aim This comprehensive literature analysis seeks to evaluate the prevalence of HPV and its notable risk factors in women aged 12 to 40 years in Saudi Arabia. Methods The review methodology adhered to PRISMA recommendations, emphasising inclusion criteria for papers containing primary and secondary data for individuals at risk for HPV. The review utilised the POE framework for database searches, extracting data from 8 electronic databases, including Educational Research Information Centre (ERIC), Academic Search Complete, PubMed/Medline, Google Scholar, Directory of Open Access Journals (DOAJ), SCOPUS, Science Direct, and Web of Science. The CASP critical appraisal technique was employed to evaluate the risk of bias in the selected studies. Results Eleven papers fulfilled the inclusion criteria, with 90% being cross-sectional and one being a cohort study. The prevalence rates of HPV in Saudi Arabia varied between 5.9% and 31.6%. Principal risk factors encompassed insufficient understanding of HPV vaccination, the knowledge of healthcare providers, and sociodemographic variables. Identified effective strategies included educational programs, regular HPV screening, and focused public health initiatives. Conclusion The review finds that HPV is a complex concern with diverse risk factors shaped by regional and sociodemographic variables. Additional investigation is required to examine the influence of sexual behaviours and sociodemographic factors on HPV transmission. This will facilitate the formulation and execution of public health policies to enhance HPV prevention and health outcomes in Saudi Arabia.11 0Item Restricted ASSOCIATION BETWEEN PARENTS’ PERCEPTIONS ABOUT HUMAN PAPILLOMAVIRUS (HPV) AND CORONAVIRUS DISEASE-19 (COVID-19) VACCINES AND THEIR DECISION TO VACCINATE THEIR CHILD AGAINST HPV(2023) Almatruk, Ziyad; Axon, David R; Warholak, TerriBACKGROUND: The WHO classified vaccine hesitancy as one of the top ten threats to global health. During the COVID-19 pandemic, many people had doubt about vaccines. The HPV can lead to several types of cancer. The COVID-19 impact on US HPV vaccination reluctance is unknown. Thus, the aim of the study is to investigate parents' perceptions of Coronavirus Disease-19 (COVID-19), the Human Papillomavirus (HPV) vaccine, and HPV vaccination decisions. METHODS: A cross-sectional observational survey was administered using Qualtrics to United States parents with at least one child aged 9–18. The survey consisted of five sections: screening, parent’s perception of general Vaccination, COVID-19, HPV, and demographics. Rasch analysis was used to evaluate the instrument reliability and validity, which included principal component analysis (PCA), scale functionality, person measure, item reliability, and person reliability. A logistic regression model with variables selected using backward elimination (p<0.05) was used to evaluate the associations between parents’ perception of COVID-19 and HPV vaccine decisions. RESULTS: The study included 508 parents. The instrument contained four domains: General Vaccination, COVID-19, HPV, and Parents’ COVID-19 Experience. Except for General Vaccination, PCA showed unidimensionality. Response options satisfied scale functionality analysis. Average person measure was 0.7±8.0 logits. Person reliability was 0.7-0.9, whereas item reliability was 0.9-1.0. Item fit ranged from 0.7-2.1. A few of the difficult items to endorse with were I trust social media and/or TV to tell me the truth about vaccines, I would have my 11 children vaccinated for COVID-19 if their school required it, vaccinating my child against HPV helps to protect others from getting HPV, and I believe the COVID-19 vaccine was approved in a reasonable amount of time. A few of the easy items to endorse were physicians’ address vaccine concerns, there are safe COVID-19 vaccines for children, and I believe in vaccines. The multivariate logistic regression model with backward elimination showed that HPV Domain (adjusted odds ratio [AOR] = 1.89, 95% CI = 1.61 – 2.21), Parents COVID-19 Experience Domain (AOR = 1.32, 95% CI = 1.18 – 1.47), and men compared to women (AOR = 2.48, 95% CI = 1.37 – 4.47) were significantly associated with parents’ planning not to vaccinate their children with HPV. CONCLUSIONS: Our research offers insight into variables associated with parents’ decisions about children’s COVID-19 and HPV vaccines. More research is needed to improve the HPV vaccine uptake.7 0Item Restricted EXPLORING THE EFFECT OF HBM CONSTRUCTS AND KNOWLEDGE ON HPV VACCINATION UPTAKE AND WILLINGNESS TO RECEIVE THE HPV VACCINE AMONG COLLEGE STUDENTS(2023) Alsulami, Fahad T; Sánchez, JesúsHPV is the most common STD in the U.S. About 43 million people with HPV infections. Although the HPV vaccine has been available for over ten years and is the most effective approach to preventing HPV infection, vaccination rates are low among college students. This study aimed to measure HPV vaccination rates, HPV and HPV vaccine knowledge, and cognitive beliefs among college students across different sociodemographic characteristics. Additionally, it aimed to assess the effect of HBM constructs on HPV vaccination uptake and the willingness of non-HPV vaccinated to get the vaccine among college students. Furthermore, it aimed to assess the effect of acculturation on the HPV vaccination uptake among foreign-born college students. A cross-sectional web-based self-administered survey was used to collect data on 2,843 eligible college students. Chi-square test, independent samples t-test, one-way ANOVA, and hierarchical logistic regression analysis were used to address the research questions. This study found that about 72% of the college students were HPV-vaccinated, and about 56% of the non-HPV vaccinated college students were willing to receive the vaccine. College students had moderate knowledge of HPV and the HPV vaccine. Hierarchical logistic regression indicated that being male, Black, 26 years old, and with a graduate degree college students, high levels of perceived severity, high levels of perceived barriers, low levels of perceived susceptibly, and low levels of cues to action were significantly associated with decreased odds of being HPV-vaccinated. Among non-HPV vaccinated college students, being male, Black, Hispanic, and Asian college students, high levels of perceived susceptibly, high levels of perceived benefits, and high levels of cues to action were significantly associated with increased odds of willingness to receive the HPV vaccine. Among foreign-born college students, the hierarchical logistic regression final model indicated that age category, perceived susceptibility to HPV, perceived barriers to receiving the HPV vaccine, and cue to receiving the HPV vaccine variables were significantly associated with the HPV vaccination uptake. The results of this study provided significant insights into the HPV vaccination behavior among college students. Further, these findings can be used to develop interventions to increase HPV vaccination rates among college students.28 0