Saudi Cultural Missions Theses & Dissertations
Permanent URI for this communityhttps://drepo.sdl.edu.sa/handle/20.500.14154/10
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Item Restricted Exploring the engagement of project leaders in organizational change management process in the AEC industry(University College London (UCL), 2024-08) Bushnag, Majed Mohammad; Natalya, SergeevaThis dissertation explores the integration of Project Management (PM) and Organizational Change Management (OCM) within the Architecture, Engineering, and Construction (AEC) industry, with a specific focus on the roles, practices, and engagement of Project Leaders (PLs) in the OCM process. The research aims to enhance understanding of how PLs contribute to OCM. Using a qualitative methodology, the study involved in-depth interviews with five senior managers to gather detailed insights. The findings reveal insufficient integration between PM and OCM, highlighting the need for more alignment between the two fields. Also, the findings reveal that PLs have a key role in OCM. However, their engagement often focus on the execution phases of change than in the strategic phases. The research underscores the necessity of engaging PLs throughout the entire OCM process and developing their change leadership skills. By studying PLs roles in OCM, this research bring to light the significant role of middle management in facilitating organizational changes (OCs) within project-based organisations (PBOs). The conclusion stresses the importance of integrating PM and OCM, adopting flexible OCM approaches, and enhancing PLs’ roles in both the strategic and execution phases of the OCM process. This research offers valuable insights for both academia and practitioners, providing a framework for enhancing PLs’ engagement in OCM, and also improving overall OCM process to implementing OCs successfully.13 0Item Restricted Nonlinear Models for Mixture Experiments Including Process Variables(University Of Southampton, 2024) Alzahrani, Shroug; Biedermann, StefanieThis present work is concerned with finding and assessing a class of models that flexibly fits data from mixture experiments and mixture-process variables experiments, and with providing guidelines for how to design mixture experiments and mixture-process variables experiments when these models are fitted. Most models in the literature are either based on polynomials and are therefore not very flexible, or have a large number of parameters that make the response surface interpretation difficult to understand. The modified fractional polynomial models are a recent class of models from the literature that are flexible and parsimonious but quite restrictive. We contribute to mixture experiments by proposing a new class of nonlinear models, the complement mixture fractional polynomial (CMFP) models, by making an additional transformation of the fractional polynomial, which results in less restrictive models while retaining (and indeed exceeding) the advantages of this class. Moreover, we suggest an extended form for the modified fractional polynomial models to fit data from mixture-process variables experiments.12 0Item Restricted Review times and clinical evidence on COVID-19 Vaccine Approvals in the US Food and Drug Administration and European Union” EMA”(Massachusetts University, 2024) Abu Rukbah, Walaa Saad; Mekary, RaniaBackground: Medication approval procedures have undergone streamlining by the Food and Drug Administration (FDA) and the European Medicines Agency (EMA). This study identifies discrepancies in evidence supplied, comparing the review times and regulations of drugs licensed by both agencies. Objective: To compare the alignment of review outcomes between the EMA and FDA for medicines approved by both agencies from 2020 to 2022. Design: By examining the FDA and EMA websites, all COVID-19 vaccines licensed from December 2020 to January 2022 were identified. Publicly available information from the FDA and EMA websites determined the COVID-19 vaccines approved by each agency. Results: In 2020-2022, the FDA licensed 3 vaccines, while the EMA licensed 5. The median review time is typically shorter in the FDA than in the EMA. Differences in regulations and processes for COVID-19 vaccines submitted to the two regulators were identified. Conclusion: The median review time for COVID-19 vaccines approved by both agencies was similar. Despite differences in regulations and processes due to the pandemic, both the FDA and EMA share the common goal of ensuring safety and efficacy.36 0Item Restricted Novel Lignin from Pine Wood Chips using Microwave-Assisted Organosolv Method(Saudi Digital Library, 2024-01-01) Aljuhani, Abdulhameed Hamed; Laybourn, AndreaThe microwave-assisted Organosolv method for lignin extraction from pine wood chips, conducted in temperatures between 165°C to 205°C, is thoroughly examined in this study. Critical insights emerge as the highest lignin yield, standing at 25.237%, is achieved at 205°C, while purity reaches its pinnacle at 88.3% when operating at 195°C. Moreover, an optimal residence time of 30 minutes was optimised to achieve maximum yields of 1.93% of lignin-rich material. Microwave technology demonstrates advantages such as rapid heating and environmental friendliness, underscoring the need for judicious temperature-energy balance. A robust lignin calibration curve has been established, facilitating the precise determination of lignin concentration, ultimately revealing a lignin content of 19.582% with an STD of ±2.3% in the initial pine wood chips. These insights could be used to promote the utilisation of lignocellulosic biomass sustainably, emphasising the significance of temperature management in practical applications.20 0