Pharmacokinetics interaction of Beta blocker agent (carvedilol) administered concomitantly with fluvastatin or rosuvastatin in rats through oral route
| dc.contributor.author | Albrahim, Abdulsatar Hijy Mohammad | |
| dc.date.accessioned | 2022-05-18T12:12:04Z | |
| dc.date.available | 2022-05-18T12:12:04Z | |
| dc.date.issued | 2017 | |
| dc.degree.department | الطب البيطري والثروة الحيوانية | |
| dc.degree.grantor | King Faisal University | |
| dc.description.abstract | Carvedilol is one of the commonly used beta blockers , concomitant administration of this medicines with other medicines’ for coronary vascular disease is common , drug interaction could be a problem specially with those inhibits the cytochrome enzymes responsible for its metabolism like statins drugs. Rosuvastatin is a known inhibitor for CYP2C6 in rats that considered as a counterpart of CYP2C9 in humans that responsible for carvedilol metabolism in large extent with other enzymes as CYP2D6. T | |
| dc.identifier.other | 718 | |
| dc.identifier.uri | https://drepo.sdl.edu.sa/handle/20.500.14154/3864 | |
| dc.language.iso | en | |
| dc.publisher | Saudi Digital Library | |
| dc.thesis.level | Masters Degree | |
| dc.title | Pharmacokinetics interaction of Beta blocker agent (carvedilol) administered concomitantly with fluvastatin or rosuvastatin in rats through oral route | |
| dc.type | Thesis |