Saudi Cultural Missions Theses & Dissertations

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Targeting oral epithelial dysplasia with antigen-specific immunity
(Abdulaziz Alboushi, 2022-12-01) Alboushi, Abdulaziz; Savelyeva, Natalia
This project aimed to establish a novel approach that these two antigens may become potential targets in OED and/or biomarkers for malignant transformation. With the broad expression of MAGED4B and FJX1 antigens in head and neck cancer, these two antigens would be potential targets in OED. MAGED4B and FJX1 antigens are expressed in OED and HNSCC with immune response against these antigens. MAGED4B and FJX1 antigens expression is prospective to be high in progressed OED. Also, the more the grading the more the expression and in the same case the immune response.
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