Saudi Cultural Missions Theses & Dissertations
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Item Restricted The Effect of Citrus Flavonoids on Endothelial Function, Blood Pressure, and Lipid Profile in Healthy Adults: A Systematic Review(University of Nottingham, 2024) Alharbi, Arwa; Dew,TristanBackground: Cardiovascular disease (CVD) is one of the leading causes of death and disability worldwide. One of the strategies for preventing cardiovascular disease biomarkers is citrus flavonoids. Objectives: To determine the effect of citrus flavonoids on endothelial function, blood pressure and lipid profile in healthy people. Methodology: PubMed, Embase, and Scopus databases were used for this systematic review. Ten randomised controlled trials targeting changes in blood pressure, endothelial function and lipid profile were selected. These studies were conducted on healthy adults between 2004 and 2024. Results: A total of 576 participants from 10 studies were discussed. These participants were healthy and were both male and female between 18 and 75 years old. The effect of citrus flavonoids on endothelial function, blood pressure, and lipid profile were the main outcomes in this review. Studies have demonstrated no significance for lipid profiles. Conversely, they indicated that citrus flavonoids could affect blood pressure and endothelial function. Conclusion: Overall, the current systematic review did not indicate the effect of citrus flavonoids on the lipid profile. Citrus flavonoids could positively affect blood pressure and endothelial function.9 0