The Ipsilateral and Contralateral fMRI responses in primary Sensory cortex to cutaneous Stimulation of the Hands' tips digit.

Abstract

The peripheral nerve receives signals from the brain to carry out specific functions involving hand movement or sensation of various objects, even comprehensive feeling pain. Moreover, the peripheral nerve injury is extremely complex and dangerous, which impacts the patient's daily life even it reduces the ability to perform normal activities and no cure treatment for that damage.Several studies explain how peripheral nerve injuries depend on primary somatosensory cortex activity (S1), although no one investigates the ipsilateral and contralateral interhemispheric responses at injuries or non-injuries hands. Some studies examined interhemispheric responses at a monkey model, and this dissertation will try to prove the animal sample has the same response in the human by testing on a non-injury hand.Moreover, this study will use an fMRI image with individual analysis data for 15 participants to display the interhemispheric response, particularly in the S1 area, and use Vibrotactile stimulators to illustrate the response.Therefore, this study aims to prove that the animal model response at the Ipsilateral and contralateral of S1 is the same as thehuman brain, and the expected result looks like the monkey model.