Investigation of the thermal effects induced by near infrared (NIR) light on skin phantoms

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Date

2024

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University of Exeter

Abstract

This study utilized tissue phantoms composed of Intralipid, synthetic melanin, and India ink to mimic the human skin layers, namely the epidermis and dermis layers. We investigated the impact of Near-Infrared (NIR) radiation on these phantoms, focusing on thermal properties and heat absorption. The goal was to identify the most accurate phantom that replicates the thermal behaviour and response to NIR radiation of human skin layers. The results provided insight into how rays are absorbed and, the resultant heat effects. It also explored the effect of adding melanin to the phantoms. This included variations in absorbed laser rays, wavelength differences, and the composition of the phantoms. Thermal imaging revealed that altering the concentration of the phantom's components, such as Intralipid, synthetic melanin, and India ink could modify its temperate distribution. The temperature absorption of the phantoms escalated with the rising concentrations of synthetic melanin and India ink. This research could enhance the comprehension of patient-specific thermal therapies.

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Keywords

- Near-Infrared (NIR) light - Thermal effects - Skin phantoms - Intralipid - Synthetic melanin - India ink - Photothermal therapy (PTT) - Epidermis and dermis layers - Optical tissue phantoms - Laser irradiation - Temperature distribution - Melanin concentration - Thermal imaging - Agar gel phantoms - Biological tissue simulation - Cancer therapy - NIR wavelength (785 nm, 808 nm, 830 nm) - Light scattering and absorption - Photothermal efficiency - Tissue temperature measurement

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