Oral squamous cell carcinoma: Erosion or invasion, that is the question!
Abstract
Abstract
Purpose: To discuss the prognostic outcomes, controversies and assessment of bone invasion in oral squamous cell carcinoma (OSCC). Materials and Methods: Literature review with critique of the relevant evidence. Results: The significance of bone invasion is unclear in OSCC, with varying definitions of bone invasion and erosion contributing to conflicting results regarding the prognostic significance of bone invasion. The majority of evidence stems from retrospective cohort studies without clear study criteria and a lack of power to draw valid conclusions. Conclusion: There are currently a lack of high-quality studies assessing bone invasion in OSCC. While there appears to be some evidence that medullary invasion is prognostic, further well- designed studies are warranted.