The Dose-Dependent Response of Silver Diamine Fluoride

Abstract

Dental caries is a significant global health concern that affects people of all ages, but children and the elderly in particular. Despite advancements in dental care, dental caries persists due to the complex interaction of multiple factors, including poor oral hygiene, sugary diets, and lack of access to dental care. Moreover, Silver diamine fluoride (SDF) is becoming a more common way to treat dental caries. SDF is a clear liquid formed of ions of silver and fluoride. Even when other treatments have failed, SDF is still able to stop tooth caries from getting worse (Ozüdolu, 2021). How well SDF works and what side effects it causes depend on concentration of it. To get the most out of SDF and keep teeth pain and discoloration to a minimum, it needs to be in the right amount. To understand how SDF works to treat tooth cavities, it is important to study how different amounts affect demineralisation. The study utilises Ion-Selective Electrodes (ISEs) to analyse the complex reaction of SDF, thereby facilitating a thorough comprehension of its underlying mechanism. The application of dilution methods was employed to examine different concentrations of SDF, so revealing their effects on the process of demineralisation. The conclusive findings provide valuable insights into the concentration-dependent effectiveness of SDF, hence illuminating its potential as a novel strategy for the management of dental caries.