Evaluating the safety of adult patients with implanted DBS devices who undergo MRI examination: A structured literature review

Abstract

Abstract Background & Rationale: It's a challenge to maintain safety in MRI environment with the constant develop of implant devices which put MRI safety at risk even with the existence of safety guidelines. implanting deep brain stimulation has increased lately and there should be an update on the safety guidelines or manufacture a MRI-combatable DBS device. Aim & Objectives: This review aimed to evaluate the safety of DBS adult patients who undergone MRI examination. This was achieved in three stages; Assessing the the generalisability of the used sequences to perform in clinical practice, assess adverse events and artefacts associated with MRI and DBS, and Critically appraise the strength of the primary research to make suggestions for future research or clinical practice. Methods: A structured literature review (SLR) was conducted and PIO framework was utilised to formulate the research question. A comprehensive searching was carried out in multiple electronic databases to search for quantitative studies that are relevant to the research question and met the inclusion and exclusion criteria. and met the inclusion and exclusion criteria. A Qualsyst tool was used to evaluate the quality of methodology in all included studies. Results: four studies met the inclusion criteria. All the studies were heterogeneous and performed different techniques outside the manufacturer and vendor guidelines to assist the safety of DBS patient. No adverse events or hazards was detected during or after the MRI scan and all studies was completed safely. Assessing the methodological quality of the studies showed two studies with moderate quality and two with poor quality. Conclusions & Implications: The new experimental protocol and techniques showed a complete safe scan for DBS patience. But the low internal and external validity affects the generalizability of the findings in clinical practise it is therefore recommended that future research should consider increasing the validity to allow reproducibility and a collaboration with manufacturer and future research is necessary to apply the new findings in practise.