Plasmon enhanced fluorescence for label free biomolecule detection

Abstract

The scope of nanotechnology is swiftly growing. It has produced a massive effect on science, especially in the fields of biotechnology, biochemical and medical science. The phenomenon of metal-enhanced fluorescence (MEF) concerns the interactions of metals surfaces with the nearby fluorophores (5–90 nm), and that have the advantage which is effects on visual properties, for example, increasing quantum yield and developing photostability, as well as shortening the lifetime of the fluorophore. Metal-enhanced fluorescence, also known as plasmon-enhanced fluorescence (PEF), is widely utilised in biosensor applications – for instance, identifying cancer cells. Moreover, this technique helps to explore unhealthy cells before they reproduce in the body.