Impact of Sjögren's Syndrome on the delivery of oral health

Abstract

Sjögren’s syndrome is an autoimmune disorder marked by the infiltration of lymphocyte and plasma cell into salivary, lacrimal and other exocrine glands leading to progressive acinar destruction. Extending beyond the more commonly recognized symptoms of oral and ocular dryness, it was only in 1960s where it received definitive confirmation through the identification of autoantibodies. This breakthrough laid the groundwork for multiorgan involvement and the potential occurrence of lymphoma. Therefore, the dental practitioner should exercise vigilance in detecting the manifestations of this disease as some patients may be on antithrombotic or immunosuppressive medications, increasing their susceptibility to infection, bleeding, adrenal crisis, and MRONJ development. Hence, conducting a comprehensive dental assessment, gathering a detailed medical history, and collaborating closely with the treating physician are essential in managing those individuals effectively.