IV Vitamin C as an Adjunctive Therapy in Sepsis and Sepsis Shock.

Abstract

In my systematic literature search, I aim to thoroughly explore the use of vitamin C, as an adjunctive therapy, in the management of sepsis and septic shock. Since the latter possess significant challenges in the practice of critical care, I believe this necessitates the exploration of other supportive therapies that enhances the patients’ outcomes. By conducting a thorough search in multiple databases, my project investigated the plausibility of using vitamin C in sepsis and septic shock and how this may influence different outcomes, most importantly, the mortality rate. Furthermore, my project will dive into a comprehensive examination of high quality randomised controlled trials (RCTs), outlining in details the process of the critical appraisal and how my conclusion is based on this analysis. Finally, the findings of this project will shed the light on the implications, future recommendations, and current unanswered questions related to the use of vitamin C. This will potentially lead to an enhancement of the patients’ care and providing innovative approaches for upcoming research as well as improving the treatment protocols in the critical care settings.