Detection and validation of Testis Expressed 19 (TEX 19) protein specific

Abstract

CTAs (cancer/testis-antigen) are a collection of tumour antigens that are mainly expressed in the testis, ovary, placenta, and germlines in normal tissues. The majority of these genes are located on the X chromosome, and they are usually found in multigene families. Diverse immunotherapy candidate genes have been discovered utilising various approaches during the previous decade.The oncogene TEX 19 has the capacity to accelerate the growth of cancer. Because of its CT gene status, TEX 19 might be utilised as a cancer biomarker for prognostic and diagnostic reasons, as well as a prospective immunotherapeutic target. This research had unexpected results in the validation and testting the specificity of an antibody designed for the TEX 19 (clone 8). Unfortunately, in this research we could not detect the TEX 19 with the designed TEX 19 antibody (clone 8). This paper will show the materials and methods used for this research.