The Impact of Prone Position on Mechanically Ventilated Patients with Covid19-ARDS, systematic review

Abstract

Background Over the last few years coronavirus has spread rampantly, effecting each nation in various ways. This virus causes acute respiratory syndrome (SARS-CoV-2) which must be aided by mechanical respiration. Prone position ventilation is a known technique that enhances oxygenation in COVID-19 patients suffering from serious acute respiratory distress syndrome (ARDS). Methodology This study conducted a systematic analysis of randomised controlled trials (RCTs) that commenced from January 2019 and onwards. The study’s purpose was to measure the effectiveness of prone position applications on individuals with mechanical ventilation who suffered from COVID-19 induced ARDS compared to those administered the supine position treatment. Results Research elected two sufficient randomised controlled trials for this study. Both studies included 452 patients who showed that application of the prone position technique correlates with a substantial enhancement in PaO2/FiO2, considerable rise in static lung compliance and insignificant variations in the extubation rate. This suggests that the prone position approach causes minimal complexities, thus is innocuous for COVID-19 patients. Prone emplacement did not considerably reduce the death rate during the 60 day time period or the length of hospital admission. Moreover, there was no meaningful influence on the 30 day period without invasive or non-invasive mechanical ventilation. No effect was stated during the 60 days without critical care observation or hospitalisation. The majority of trials explained that there was discomfort or musculoskeletal pain from the prone emplacement and desaturation. Conclusion Prone position application for COVI-19 induced ARDS is a safe and effective practice in patients with severe hypoxemic respirational malfunction. Despite prone posture being ineffective in limiting endotracheal intubation requirements compared to typical care that did not implement the prone emplacement, the clinical advantages of prone posture are significant.