MIDDLE MESIAL CANAL DETECTION IN MANDIBULAR PERMANENT MOLARS USING MANUAL VERSUS SEMIAUTOMATIC SEGMENTATION OF CBCT SCANS (IN VITRO STUDY)
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Date
2026
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Journal ISSN
Volume Title
Publisher
Saudi Digital Library
Abstract
*Background: Technological advancements are improving medical practices in dentistry,
leading to favorable changes in dental operations. Cone beam computed tomography (CBCT)
is a cutting-edge technique for creating three-dimensional images. It offers a noninvasive way
to examine intricate root canal structures.
Objectives: This study aimed to assess the accuracy of identifying the middle mesial canal
(MMC) in mandibular molars using manual and semiautomated pulpal segmentation of
CBCT scans, along with the clearing technique.
*Methods: A diagnostic accuracy in vitro study was conducted on 48 extracted first and
second mandibular permanent molars obtained from the Oral and Maxillofacial Surgery
Department at Alexandria University. The molars were placed in a human cadaver mandible
and analyzed to identify the MMC using periapical digital radiography, manual,
semiautomated, and automated CBCT segmentation, and the clearing technique (gold
standard). Sensitivity, specificity, and accuracy of all methods were collected and volumetric
analysis and time were analyzed using repeated measures ANOVA, followed by multiple
pairwise comparisons using Bonferroni correction, with a significance level set at P<0.05.
*Results: A MMC was detected in two out of the 48 teeth. Digital radiography showed 0%
sensitivity and 100% specificity, with an overall accuracy of 95.83%. Manual,
semiautomated, and automated CBCT analyses achieved 100% sensitivity and specificity for
detecting the two MMC compared to the clearing technique. Manual segmentation took
significantly more time (71.56 minutes) compared to semiautomated (22.48 minutes) and
automated (0.20 minutes) methods (p < 0.001). No significant differences in volume
measurements were noted among the three methods.
*Conclusion: CBCT provided greater sensitivity, specificity, and accuracy in identifying
MMC compared to digital radiography. Semiautomated and automated segmentation offers
significant time saving and accuracy over manual methods.
Description
Keywords
CBCT, Clearing technique, Diagnostic Accuracy, Digital periapical radiograph, first mandibular molar, Middle mesial canal, Semi-automated segmentation., Artificial Intelligence
