Moisture migration in Alginate-based Wound Dressings
No Thumbnail Available
Date
2025
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Saudi Digital Library
Abstract
Precise and sensitive quantification of the moisture migration behavior of alginate moist wound dressings within an environment analogous to one of its end use is challenging to simulate, largely due to alginates’ high susceptibility to swelling. This study utilised the gravimetric method, chiefly the dry cup method outlined by the ASTM E 96 standard, to investigate and compare the rate of moisture vapor transmission, %moisture content, and permeability parameters through the moist wound dressings: Algisite M, Cutiderm, Kaltostat and Tegaderm in different simulated environments for accurate characterisation within a simulated environment closely resembling the biological context of their application, at 37 °C and RH% conditions adjusted based on the data to be extracted being diffusion or water sorption.
Description
This study quantifies and compares the moisture vapor transmission loss and moisture vapor permeability of various alginate wound dressings on the market, to best match their uses for specific wound types and depths. MVTR and MVP values are extrapolated from diffusion plots produced using the dynamic vapor sorption analyser via the gravimetric method. The DVS analyser was utilised to quantify moisture loss and gain of the wound dressings sensitive to the 4th decimal point, at average body temperature, varying relative humidity to emulate the environment in which its used.
Keywords
moisture migration, MVTR, MVTR measurement, MVTR quantification, moisture, moisture vapor transmission rate, wvtr, water vapor transmission rate, alginate, alginate wound dressing, wound dressing, moist wound healing, DVS, Dynamic vapor sorption, dynamic vapor sorption analyser, gravimetric method, moist wound healing environment, dry cup method, desiccant method, biological conditions, algisite M, cutiderm, kaltostat, tegaderm, semipermeable film, relative humidity, RH%, diffusion, exudate, water sorption, water sorption isotherm, payne cell, mvp, moisture vapor permeaility, diffusion plot, permeance, tewl, trans epidermal water loss
Citation
MLA 9