Moisture migration in Alginate-based Wound Dressings

Abstract

Precise and sensitive quantification of the moisture migration behavior of alginate moist wound dressings within an environment analogous to one of its end use is challenging to simulate, largely due to alginates’ high susceptibility to swelling. This study utilised the gravimetric method, chiefly the dry cup method outlined by the ASTM E 96 standard, to investigate and compare the rate of moisture vapor transmission, %moisture content, and permeability parameters through the moist wound dressings: Algisite M, Cutiderm, Kaltostat and Tegaderm in different simulated environments for accurate characterisation within a simulated environment closely resembling the biological context of their application, at 37 °C and RH% conditions adjusted based on the data to be extracted being diffusion or water sorption.