The Effect of Citrus Flavonoids on Endothelial Function, Blood Pressure, and Lipid Profile in Healthy Adults: A Systematic Review

dc.contributor.advisorDew,Tristan
dc.contributor.authorAlharbi, Arwa
dc.date.accessioned2025-01-23T06:01:35Z
dc.date.issued2024
dc.descriptionTo investigate the positive effects of citrus flavonoids on endothelial function, lipid profile, and blood pressure among healthy adults. Researchers may focus on prevention rather than treatment by looking at these markers in healthy adults. This is consistent with the increased emphasis on preventative medicine and overall health. Studying these characteristics in healthy people can provide a more detailed mechanistic understanding of how citrus flavonoids affect heart health without the complicating elements encountered in pathological situations
dc.description.abstractBackground: Cardiovascular disease (CVD) is one of the leading causes of death and disability worldwide. One of the strategies for preventing cardiovascular disease biomarkers is citrus flavonoids. Objectives: To determine the effect of citrus flavonoids on endothelial function, blood pressure and lipid profile in healthy people. Methodology: PubMed, Embase, and Scopus databases were used for this systematic review. Ten randomised controlled trials targeting changes in blood pressure, endothelial function and lipid profile were selected. These studies were conducted on healthy adults between 2004 and 2024. Results: A total of 576 participants from 10 studies were discussed. These participants were healthy and were both male and female between 18 and 75 years old. The effect of citrus flavonoids on endothelial function, blood pressure, and lipid profile were the main outcomes in this review. Studies have demonstrated no significance for lipid profiles. Conversely, they indicated that citrus flavonoids could affect blood pressure and endothelial function. Conclusion: Overall, the current systematic review did not indicate the effect of citrus flavonoids on the lipid profile. Citrus flavonoids could positively affect blood pressure and endothelial function.
dc.format.extent45
dc.identifier.urihttps://hdl.handle.net/20.500.14154/74724
dc.language.isoen
dc.publisherUniversity of Nottingham
dc.subjectCitrus
dc.subjecthesperidin
dc.subjectcitrus flavonoids
dc.subjectendothelial function
dc.subjectFMD
dc.subjectblood pressure
dc.subjectlipid profile.
dc.titleThe Effect of Citrus Flavonoids on Endothelial Function, Blood Pressure, and Lipid Profile in Healthy Adults: A Systematic Review
dc.typeThesis
sdl.degree.departmentClinical Nutrition
sdl.degree.disciplineClinical Nutrition
sdl.degree.grantorUniversity of Nottingham
sdl.degree.namethe degree of Masters Science in [MSc Clinical Nutrition]

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